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Risk factors for post-ERCP pancreatitis and hyperamylasemia: A retrospective single-center study

Authors :
Qi Bin He
Xiao Ping Zou
Te Xu
Yun Hong Li
Lei Wang
Jing Wang
Source :
Journal of Digestive Diseases. 16:471-478
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

Objective With an increased use of endoscopic retrograde cholangiopancreatography (ERCP), post-ERCP complications have attracted much attention. We aimed to identify independent risk factors of post-ERCP pancreatitis (PEP) and hyperamylasemia, and to develop a simple scoring system of the factors contributing to the clinical prevention against PEP. Methods A retrospective single-center analysis was performed in 4234 ERCP procedures between September 2007 and December 2012. Patient-related and procedure-related risk factors for PEP and post-ERCP hyperamylasemia were identified by univariate and multivariate regression analyses. A scoring system was developed based on the independent risk factors. Results PEP occurred in 226 (5.3%) ERCP procedures and hyperamylasemia in 774 (18.3%) procedures. Female gender (odds ratio [OR] 1.449), first-time ERCP (OR 1.745), latent jaundice (OR 1.917), difficult cannulation (OR 3.317) and pancreatography (OR 1.823) were all proven to be significant risk factors for predicting PEP. In addition, difficult cannulation (OR 1.990) and pancreatography (OR 2.009), age

Details

ISSN :
17512972
Volume :
16
Database :
OpenAIRE
Journal :
Journal of Digestive Diseases
Accession number :
edsair.doi...........44bc3b0d40661d2c895894cada32b467
Full Text :
https://doi.org/10.1111/1751-2980.12258