INVESTIGATION OF IMMUNOTOXICITY AND ALLERGENIC PROPERTIES OF DRY EXTRACT OF POTENTILLA ALBA L

The comprehensive study of allergenicity and immunotoxicity of dry extract of Potentilla alba L. has shown that the extract has no sensitizing effect in tests of the general systemic anaphylaxis (anaphylactic shock) and active skin anaphylaxis conducted on Guinea pigs albinos, as well as in the reaction of delayed hypersensitivity in mice. In the study of immunotoxic properties, it has been found that the extract has a stimulating effect on the primary humoral immune response at a therapeutic dose of 3 mg / kg and has no influence on the effectors of the cellular immunity of experimental animals.