Thrombolysis as a factor associated with favorable outcomes in patients with unclear-onset stroke

Background and purpose: Clinical and radiological features of patients with unclear-onset stroke do not differ significantly from those with known-onset stroke. There is a lack of evidence for the safety and efficacy of thrombolysis in patients with unclear-onset stroke. We sought to provide supportive data on the safety and efficiency of thrombolysis in patients with unclear-onset stroke. Methods: We retrospectively identified patients with unclear-onset stroke (