An efficient route to C-4 linked imidazole nucleosides : synthesis of 2-carbamoyl-4-(2′-deoxy-β-d-ribofuranosyl)imidazole

The first synthesis of an imidazole C-nucleoside linked through C-4, 2-carbamoyl-4-(2′-deoxy-β-d-ribofuranosyl)imidazole was achieved by way of a nine-step sequence starting from 2-deoxy-3,5-di-O-p-toluoyl-d-erythro-pentofuranosyl chloride.