ChemInform Abstract: Three Substituted 3-Amino-2-benzoylaminopropenoic Acid Derivatives

The molecular structures of three substituted 3-amino-2-benzoylaminopropenoic acid derivatives, methyl (Z)-2-benzoylamino-3-dimethylaminopropenoate (A), methyl (Z)-2-benzoylamino-3-(4,6-dimethyl-2-pyrimidinylamino)propenoate (B) and N-[(Z)-2-benzoylamino-3-(4,6-dimethyl-2-pyrimidinylamino)propenoyl]-L-proline monohydrate (C), show that the configuration around the exocyclic C=C double bond is Z. The mechanisms of syntheses of (B) and (C) from (A) are confirmed as the Z configuration is preserved in the title compounds