Isolated Clivus Metastasis as the First Presentation of Relapse Breast Cancer: A Case Report and Literature Review

The clivus is situated at an anatomically critical location next to brainstem and the majority of the cranial nerves and involved in approximately 1% of intracranial tumors. Isolated metastase to clivus have been rarely reported in breast cancer. We report a case of 58 year old women, who present a cranialnerve palsy as the first presentation of isolated clival metastasis in a treated patient of breast cancer. The etiology was obteined by brain CT, magnetic resonance imaging (MRI) which showed lesion in the clivus. The diagnosis of clival metastasis from breast cancer was confirmed by transsphenoidal biopsy. The patient received radiotherapy with corticotherapy with favorable evolution within 5 days.