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Additional file 2: Figure S2. of α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
- Publication Year :
- 2018
- Publisher :
- figshare, 2018.
-
Abstract
- The schematic diagram depicts the time schedule of intervention and analyses performed. Numerals represent the days experiments were conducted. On 1th day we injected saline or MPTP (2 h interval, 4 times, 20 mg/kg free base) in 8 months WT, GBA +/L444P , SNCA−/−, GBA +/L444P SNCA−/− mice. On 6th day, the pole and grip strength were performed. On 7th day, mice were sacrificed for indicated studies. Following are animal numbers used for these studies: behavioral (n = 10), neurochemical (n = 5), immunohistochemistry (n = 5), and biochemical studies (n = 4) per each treatment group. (PDF 110 kb)
- Subjects :
- 3. Good health
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........48b9477cd001bc9be238737294f9fe2c
- Full Text :
- https://doi.org/10.6084/m9.figshare.5768985.v1