Changes in basal insulin secretion capacity after pancreatectomy: a single-center retrospective study

Background This study evaluated the changes in basal insulin secretion capacity (BISC) after pancreatectomy across two surgical procedures. We also investigated the association between decreased BISC and the introduction of postoperative insulin therapy. Methods The data on 110 patients who underwent pancreatectomy during October 2018–February 2022 at our hospital were retrospectively registered and analyzed. We focused on the C-peptide index (CPI) as an index for BISC. A decreased postoperative BISC was defined as a postoperative CPI (post-CPI)