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A Facile One-Step Synthesis of Ethyl 2-(L,L-Dialkyl and Arylmethyl) Malonates

Authors :
Michael B. Smith
Sung Kee Chung
Tae-Woo Kwon
Young Mee Kim
Source :
Synthetic Communications. 29:343-350
Publication Year :
1999
Publisher :
Informa UK Limited, 1999.

Abstract

Diethyl ethoxymethylenemalonate (EMME) is unexpectedly converted into diethyl 2-(1,1 -dialkyl and diarylmethyl) malonate derivatives by a classical Grignard reaction. Addition of organocuprates to EMME gave diethyl 2-(l-ethoxyalkyl) malonate derivatives. The yields range from 42-63%.

Details

ISSN :
15322432 and 00397911
Volume :
29
Database :
OpenAIRE
Journal :
Synthetic Communications
Accession number :
edsair.doi...........49d06e4c9b657dc9f23b03d8385350bd
Full Text :
https://doi.org/10.1080/00397919908085773