ChemInform Abstract: SYNTHESIS OF NEOBAVAISOFLAVONE

Condensation of 7-benzoyldaidzein (III) with 2-methyl-3-buten-2-ol gave 7-benzoyl-3′-(3-methyl-2-butenyl)daidzein (IV). Hydrolysis of IV with dilute alkali gave 3′-(3-methyl-2-butenyl)daidzein (neobavaisoflavone) (I), which was converted into isoneobavaisoflavone (VI) when heated with formic acid. 7-Benzyldaidzein (VII) was condensed with 2-methyl-3-buten-2-ol to give a chroman derivative (VIII), which was converted into VI by hydrogenolysis.