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Dynamic contrast-enhanced MRI, diffusion-weighted MRI and 18F-FDG PET/CT for the prediction of survival in oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiation
- Source :
- European Radiology. 26:4162-4172
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- We prospectively investigated the roles of pretreatment dynamic contrast-enhanced MR imaging (DCE-MRI), diffusion-weighted MR imaging (DWI) and 18F-fluorodeoxyglucose-positron emission tomography (18F-FDG PET)/CT for predicting survival of oropharyngeal or hypopharyngeal squamous cell carcinoma (OHSCC) patients treated with chemoradiation. Patients with histologically proven OHSCC and neck nodal metastases scheduled for chemoradiation were eligible. Clinical variables as well as DCE-MRI-, DWI- and 18F-FDG PET/CT-derived parameters of the primary tumours and metastatic neck nodes were analysed in relation to 3-year progression-free survival (PFS) and overall survival (OS) rates. Eighty-six patients were available for analysis. Multivariate analysis identified the efflux rate constant (K ep)-tumour
- Subjects :
- medicine.medical_specialty
medicine.diagnostic_test
business.industry
Head and neck cancer
Ultrasound
Interventional radiology
Hypopharyngeal cancer
General Medicine
medicine.disease
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Text mining
030220 oncology & carcinogenesis
Dynamic contrast-enhanced MRI
medicine
Radiology, Nuclear Medicine and imaging
Radiology
business
Diffusion MRI
Neuroradiology
Subjects
Details
- ISSN :
- 14321084 and 09387994
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- European Radiology
- Accession number :
- edsair.doi...........4aa7a613b79815537fb5ff6e2409d478