Metal-free oxidative C(sp3)–H functionalization: a facile route to quinoline formaldehydes from methyl-azaheteroarenes

A facile protocol for the synthesis of quinoline formaldehydes via direct oxidative C–H bonds functionalization of methyl-azaheteroarenes in the presence of I2–DMSO has been described. This method is metal-free and easy to operate. This reaction provided a convenient route for the preparation of a range of important quinoline formaldehydes.