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New C-19-Substituted Lappaconitine Derivatives

Authors :
T. M. Gabbasov
E. M. Tsyrlina
M. S. Yunusov
Leonid V. Spirikhin
Source :
Chemistry of Natural Compounds. 57:1066-1073
Publication Year :
2021
Publisher :
Springer Science and Business Media LLC, 2021.

Abstract

New lappaconitine, N-deacetyllappaconitine, and lappaconine derivatives with C-19 C–C-bonded substituents were prepared from lappaconitine–isoxazolidine hybrids by reductive and oxidative opening of isoxazolidine rings annelated to the lappaconitine N(20)–C(19) bond.

Details

ISSN :
15738388 and 00093130
Volume :
57
Database :
OpenAIRE
Journal :
Chemistry of Natural Compounds
Accession number :
edsair.doi...........4c4190e85161dc0b899fee2085873b59