Therapeutic effect of Chinese Tuina on diabetic peripheral neuropathy: a systematic review and meta-analysis

Review question / Objective: Diabetic peripheral neuropathy (DPN) is one of the chronic microvascular complications of diabetes mellitus (DM). Chinese Tuina is a promising external treatment of traditional Chinese medicine (TCM), which can promote blood circulation, increase the support of tissues, accelerate metabolism and facilitate the improvement of neurological function, thereby improving the quality of life of patients with DPN. Although increasing clinical studies reveals the efficacy of Chinese Tuina therapy and its safety on DPN patients, whether Chinese Tuina therapy is indeed improving DPN remains unclear. In this study, we intended to evaluate the clinical efficacy and safety of Chinese Tuina in the treatment of DPN. Patient, Participant, or population: Inclusion criteria: Patients with diabetic peripheral neuropathy (diagnosed clinically using any accepted diagnostic criteria).