Back to Search
Start Over
DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial
- Source :
- The American Journal of Clinical Nutrition. 97:1134-1143
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- Background: Docosahexaenoic acid (DHA) is important for brain function, and its status is dependent on dietary intakes. Therefore, individuals who consume diets low in omega-3 (n23) polyunsaturated fatty acids may cognitively benefit from DHA supplementation. Sex and apolipoprotein E genotype (APOE) affect cognition and may modulate the response to DHA supplementation. Objectives: We investigated whether a DHA supplement improves cognitive performance in healthy young adults and whether sex and APOE modulate the response. Design: Healthy adults (n = 176; age range: 18‐45 y; nonsmoking and with a low intake of DHA) completed a 6-mo randomized, placebo-controlled, double-blind intervention in which they consumed 1.16 g DHA/d or a placebo. Cognitive performance was assessed by using a computerized cognitive test battery. For all tests, z scores were calculated and clustered into cognitive domains as follows: episodic and working memory, attention, reaction time (RT) of episodic and working memory, and attention and processing speed. ANCOVAwas conducted with sex and APOE as independent variables. Results: RTs of episodic and working memory improved with DHA
- Subjects :
- Apolipoprotein E
chemistry.chemical_classification
Nutrition and Dietetics
business.industry
Working memory
Medicine (miscellaneous)
Physiology
Cognition
law.invention
chemistry
Randomized controlled trial
Docosahexaenoic acid
law
Medicine
lipids (amino acids, peptides, and proteins)
Effects of sleep deprivation on cognitive performance
business
Episodic memory
Polyunsaturated fatty acid
Subjects
Details
- ISSN :
- 00029165
- Volume :
- 97
- Database :
- OpenAIRE
- Journal :
- The American Journal of Clinical Nutrition
- Accession number :
- edsair.doi...........4ef22f35403ccd619c831ab3a097314c