Back to Search
Start Over
First screening ofAedes albopictusimmunogenic salivary proteins
- Source :
- Insect Molecular Biology. 22:411-423
- Publication Year :
- 2013
- Publisher :
- Wiley, 2013.
-
Abstract
- Study of the human antibody (Ab) response to Aedes salivary proteins can provide new biomarkers to evaluate human exposure to vector bites. The identification of genus- and/or species-specific proteins is necessary to improve the accuracy of biomarkers. We analysed Aedes albopictus immunogenic salivary proteins by 2D immunoproteomic technology and compared the profiles according to human individual exposure to Ae. albopictus or Ae. aegypti bites. Strong antigenicity to Ae. albopictus salivary proteins was detected in all individuals whatever the nature of Aedes exposure. Amongst these antigenic proteins, 68% are involved in blood feeding, including D7 protein family, adenosine deaminase, serpin and apyrase. This study provides an insight into the repertoire of Ae. albopictus immunogenic salivary proteins for the first time.
- Subjects :
- Aedes
0303 health sciences
Saliva
Antigenicity
Aedes albopictus
biology
Protein family
fungi
030231 tropical medicine
virus diseases
Serpin
biology.organism_classification
Virology
3. Good health
03 medical and health sciences
0302 clinical medicine
Antigen
Insect Science
Genetics
biology.protein
Antibody
Molecular Biology
030304 developmental biology
Subjects
Details
- ISSN :
- 09621075
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Insect Molecular Biology
- Accession number :
- edsair.doi...........5090e7144ee230d131c972c58500ee65