A Software Architecture for Developing Disease Registries

This paper proposes a novel software architecture for developing disease registries. Our proposal consists of five horizontal layers and two transversal layers. It takes into account several aspects of disease registries, such as various sources of data acquisition, security and privacy issues, data analytics, and user management tasks. Several use cases are presented: the Tunisian Fanconi Anemia Registry (TFAR), the Tunisian Gaucher Disease Registry (TGDR), the Tunisian Non-Hodgkin Lymphoma Registry (TNHLR), and the Tunisian Registry of Diabetes Type 1 (TRD-T1).