Back to Search Start Over

Improvement effect of a next-generation probiotic L. plantarum-pMG36e-GLP-1 on type 2 diabetes mellitus via the gut–pancreas–liver axis

Authors :
Hong Hu
Jie Luo
Ying Liu
Hongyu Li
Rui Jin
Shengjie Li
Jing Wei
Hong Wei
Tingtao Chen
Source :
Food & Function. 14:3179-3195
Publication Year :
2023
Publisher :
Royal Society of Chemistry (RSC), 2023.

Abstract

A next-generation probiotic Lactobacillus plantarum-pMG36e-GLP-1 was constructed to express GLP-1 in vivo, which may affect the gut-pancreas-liver axis, thereby relieving the symptoms of HFD/STZ-induced T2DM mice and db/db mice.

Subjects

Subjects :
General Medicine
Food Science

Details

ISSN :
2042650X and 20426496
Volume :
14
Database :
OpenAIRE
Journal :
Food & Function
Accession number :
edsair.doi...........51acd0c1225fb7e01a09030f1d21f793