Light-mediated direct transformation of 2-chloro-propiophenones into 2-arylpropionic acids

Authors :: Nagaraj R. Ayyangar
Dilip G. Kulkarni
Harikisan R. Sonawane
Source :: Tetrahedron Letters. 31:7495-7496
Publication Year :: 1990
Publisher :: Elsevier BV, 1990.
Abstract: A strategy based on photochemical 1,2-aryl migration as the pivotal step allows efficient transformation of 2-chloro-propiophenones into 2-arylpropionic acids. A noticeable substituent-directed excited state control on the rearrangement process has been observed.

Subjects :: chemistry.chemical_classification
Propiophenones
chemistry
Stereochemistry
Excited state
Carboxylic acid
Organic Chemistry
Drug Discovery
Biochemistry
Haloketone
Combinatorial chemistry
Direct transformation

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