Studies on Cyanide and Thiocyanate in Uraemia

Cyanide and thiocyanate was measured in blood and in peritoneal lavage solution in patients with advanced or terminal renal failure. The behavior of these substances was comparable to that of normal people. Our finding does not support the hypothesis of an indirect toxicity of urea via its previous conversion to cyanate. Cyanate ion has not been implicated in the toxic status of chronic uraemia.