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Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
- Source :
- Journal of Biological Engineering. 17
- Publication Year :
- 2023
- Publisher :
- Springer Science and Business Media LLC, 2023.
-
Abstract
- Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regeneration to restore blood circulation. As biomedical research has evolved rapidly, a variety of potential alternative therapeutics has been explored widely, such as growth factor-based therapy, cell-based therapy, and material-based therapy including nanomedicine and biomaterials. This review will comprehensively describe the main pathogenesis of vascular injury in ischemic vascular disease, the therapeutic function of the above three treatment strategies, the corresponding potential challenges, and future research directions.
- Subjects :
- Environmental Engineering
Biomedical Engineering
Cell Biology
Molecular Biology
Subjects
Details
- ISSN :
- 17541611
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Journal of Biological Engineering
- Accession number :
- edsair.doi...........544c04bc56952b42ada43fd4abff882b