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The Reaction of 16-Hydroxymethylene-17-keto Steroids with Semicarbazide and Thiosemicarbazide to Give 17α-Hydroxy[17β,16β-c]-Δ1'(5')-pyrazoline Derivatives. 17α-Hydroxy-3-methoxy-2'-thiocarbamoylestra-1,3,5(10)-trieno[17β, 16β-c]-Δ1'(5')-pyrazoline, a Potential Nonfeminizing Hypocholesterolemic Agent

The Reaction of 16-Hydroxymethylene-17-keto Steroids with Semicarbazide and Thiosemicarbazide to Give 17α-Hydroxy[17β,16β-c]-Δ1'(5')-pyrazoline Derivatives. 17α-Hydroxy-3-methoxy-2'-thiocarbamoylestra-1,3,5(10)-trieno[17β, 16β-c]-Δ1'(5')-pyrazoline, a Potential Nonfeminizing Hypocholesterolemic Agent

Authors :
Martin J. Weiss
Robert E. Schaub
Jan H. van den Hende
Source :
The Journal of Organic Chemistry. 30:2234-2240
Publication Year :
1965
Publisher :
American Chemical Society (ACS), 1965.

Details

ISSN :
15206904 and 00223263
Volume :
30
Database :
OpenAIRE
Journal :
The Journal of Organic Chemistry
Accession number :
edsair.doi...........545318ea74f413d9a4d6acce9ead7931
Full Text :
https://doi.org/10.1021/jo01018a028