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Changes in Alpha-fetoprotein, Phosphorus, Calcium, and Metabolic Hormones in Goats had Singleton, Twin, and Triplet Pregnancy

Authors :
Mohamed kandil
Sally Ibrahim
Omnia El-sayed
M Karima Ghoneimy
Mahmoud Abou El-Roos
Source :
Egyptian Journal of Veterinary Sciences. 53:15-23
Publication Year :
2022
Publisher :
Egypts Presidential Specialized Council for Education and Scientific Research, 2022.

Abstract

The present study aimed to clarify the alternations in alpha-fetoprotein (AFP), phosphorus (Ph), calcium (Ca), and metabolic hormones (Growth hormones (GH), insulin, and thyroid gland hormones) in singleton, twin, and triplet pregnancy in goats. Animals were examined for pregnancy ultrasonographically during mid-pregnancy (6-14 weeks of gestation), and were classified conferring to litter size into singleton (n =55), twin (n=25) and triple (n=6) pregnancy, and non-pregnant status (n=64). Blood samples (5 ml) were collected before ultrasound examination and serum was separated for analysis of alpha-fetoprotein, phosphorus, calcium, and GH, insulin, T3, and T4. The current data showed that the fetal numbers markedly influenced AFP, Ph, Ca, GH, insulin, T3 levels, but did not affect T4 and Ph/Ca ratio. AFP levels were higher in twin (P< 0.05) and triple (P< 0.001) bearing does than in non-pregnant does (56.00±5.00 and 87.00±1.90 vs 3.80±.051 ng/ml). Phosphorus and Ca levels declined with pregnancy, with the substantial decreased in multiple feti compared with non-pregnant does. Growth hormone imminently raised in twine and triple fetuses than non-pregnant does. Insulin levels elevated in triple compared to non- pregnant and singleton (P< 0.005). Serum free T3 levels were lower in single and twin bearing does than non-pregnancy. In conclusion, fetal number markedly influenced the dam metabolic profile and mineral homostatis through altering AFP and metabolic hormones levels during pregnancy in goats.

Details

ISSN :
2357089X
Volume :
53
Database :
OpenAIRE
Journal :
Egyptian Journal of Veterinary Sciences
Accession number :
edsair.doi...........54b7fb59e8870a2d7a9a0a192e1a691d
Full Text :
https://doi.org/10.21608/ejvs.2021.84970.1249