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Phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti-programmed cell death ligand-1 (PD-L1) antibody, in myelodysplastic syndrome (MDS) after treatment with hypomethylating agents

Authors :
Ronald Paquette
Jonathan D. Norton
Lucy A. Godley
Robert Coleman Lindsley
Uwe Platzbecker
Charles A. Schiffer
Guillermo Garcia-Manero
Joyson Joseph Karakunnel
Paul B. Robbins
Source :
Journal of Clinical Oncology. 33:TPS7103-TPS7103
Publication Year :
2015
Publisher :
American Society of Clinical Oncology (ASCO), 2015.

Abstract

TPS7103 Background: Myelodysplastic syndrome (MDS) is a group of clonal bone marrow disorders associated with an increased risk of transformation to acute myeloid leukemia (AML). Despite recent pro...

Details

ISSN :
15277755 and 0732183X
Volume :
33
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........566364486fbbfa55625d252eca5fb064
Full Text :
https://doi.org/10.1200/jco.2015.33.15_suppl.tps7103