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ChemInform Abstract: Organocatalytic Asymmetric Wittig Reactions: Generation of Enantioenriched Axially Chiral Olefins Breaking a Symmetry Plane

Authors :
Giacomo Filippini
Mariafrancesca Fochi
Lucia Gramigna
Luca Bernardi
Sara Duce
Mauro Comes Franchini
Source :
ChemInform. 43
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

It is demonstrated, that the stereochemical outcome of Wittig olefinations of 4-substituted cyclohexanones can be controlled by hydrogen-bond donor catalysts such as (R,R)-TADDOL or 1,2-diaminocyclohexane derived bis-thioureas.

Details

ISSN :
09317597
Volume :
43
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........5773d9d68ff0e51becc342cee568be39
Full Text :
https://doi.org/10.1002/chin.201213059