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Identification of potent siRNA targeting complement C5 and its robust activity in pre-clinical models of myasthenia gravis and collagen-induced arthritis

Authors :
Yoshikazu Kuboi
Yuta Suzuki
Sotaro Motoi
Chiyuki Matsui
Naoki Toritsuka
Tomoya Nakatani
Kazuhiro Tahara
Yoshinori Takahashi
Yoko Ida
Ayaka Tomimatsu
Motohiro Soejima
Toshio Imai
Source :
Molecular Therapy - Nucleic Acids. 31:339-351
Publication Year :
2023
Publisher :
Elsevier BV, 2023.

Subjects

Subjects :
Drug Discovery
Molecular Medicine

Details

ISSN :
21622531
Volume :
31
Database :
OpenAIRE
Journal :
Molecular Therapy - Nucleic Acids
Accession number :
edsair.doi...........57fa0d92b4a8003ee0ad89977ea55b9d
Full Text :
https://doi.org/10.1016/j.omtn.2023.01.005