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Brønsted-Acid-Catalyzed (3+2)-Cycloannulation of In-Situ-Generated 3-Methide-3H-pyrroles: Asymmetric Synthesis of Cyclopenta[b]pyrroles
- Source :
- Organic Letters. 22:9065-9070
- Publication Year :
- 2020
- Publisher :
- American Chemical Society (ACS), 2020.
-
Abstract
- An organocatalytic, highly enantioselective addition of cyclic enamides to in-situ-generated 3-methide-3H-pyrroles with subsequent cyclization and elimination has been developed. This protocol repr...
Details
- ISSN :
- 15237052 and 15237060
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Organic Letters
- Accession number :
- edsair.doi...........599c53706c791e43453f74323360d3ee
- Full Text :
- https://doi.org/10.1021/acs.orglett.0c03452