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Structure prediction algorithm for protein complexes based on gene ontology

Authors :
Ilya A. Vakser
Alexander V. Tuzikov
Ivan Anishchenko
A. Yu. Hadarovich
Petras J. Kundrotas
Source :
Doklady of the National Academy of Sciences of Belarus. 64:150-158
Publication Year :
2020
Publisher :
Publishing House Belorusskaya Nauka, 2020.

Abstract

We propose an algorithm for comparing protein-protein complexes based on their functional properties in terms of Gene Ontology. The proposed measure of a functional similarity between complexes is combined with a structural measure to find templates for the template-based docking of protein complexes. We present the results on the modeling of protein complexes based on this algorithm.

Details

ISSN :
25242431 and 15618323
Volume :
64
Database :
OpenAIRE
Journal :
Doklady of the National Academy of Sciences of Belarus
Accession number :
edsair.doi...........5a0a7a9f8db87fbec63919c9a3095764
Full Text :
https://doi.org/10.29235/1561-8323-2020-64-2-150-158