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ChemInform Abstract: Asymmetric Synthesis of δ-Chloro-β-amino-N-sulfinyl Imidates as Versatile Chiral Building Blocks for the Synthesis of 2,3-Disubstituted Piperidines

Authors :
Sven Mangelinckx
Norbert De Kimpe
Elena Semina
Kristof Van Hecke
Filip Colpaert
Source :
ChemInform. 46
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

New β-amino-δ-chloro carboximidates bearing a chiral sulfoxide auxiliary are prepared and used as building blocks for the synthesis of enantio- and diastereomeric pure 2,3-disubstituted piperidines (similar reactions based on the minor diastereomer are not shown).

Details

ISSN :
09317597
Volume :
46
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........5a43adbad8a45c3189e79bdb1c1c44b2
Full Text :
https://doi.org/10.1002/chin.201547165