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Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the <scp>C</scp> ardio‐ <scp>O</scp> ncology <scp>S</scp> tudy <scp>G</scp> roup of the <scp>H</scp> eart <scp>F</scp> ailure <scp>A</scp> ssociation of the <scp>E</scp> uropean <scp>S</scp> ociety of <scp>C</scp> ardiology in collaboration with the <scp>I</scp> nternational <scp>C</scp> ardio‐ <scp>O</scp> ncology <scp>S</scp> ociety

Authors :
Johann Bauersachs
Petar M. Seferovic
Teresa López-Fernández
Ovidiu Chioncel
Ronald M. Witteles
Michael G. Fradley
Bonnie Ky
Daniel J. Lenihan
Thomas Thum
Dragana Milojkovic
Paaladinesh Thavendiranathan
Javid Moslehi
Michael J. Mauro
Frank Ruschitzka
Thomas M. Suter
John D. Groarke
Jutta Bergler-Klein
Charlotte Manisty
Li Ling Tan
Vincent Khoo
Ariane Vieira Scarlatelli Macedo
Radek Pudil
Ashutosh Wechelaker
Dimitrios Farmakis
Y N Belenkov
Susan Dent
Hugues de Lavallade
Chris Plummer
Susannah Stanway
Alain Cohen-Solal
Tomas G. Neilan
Alexander R. Lyon
Fortunato Ciardiello
Andrew J.S. Coats
M. Sol Andres
Daniela Cardinale
Hadi Skouri
David Wright
Ana Barac
Christoph Maack
Stuart D. Rosen
Christine Brezden-Masley
Zaza Iakobishvili
Robert F. Cornell
Markus S. Anker
Aaron L. Sverdlov
Helena M. Earl
Carlo G. Tocchetti
Ludhmila Abrahão Hajjar
Stephan von Haehling
Joerg Herrmann
Rudolf A. de Boer
Source :
European Journal of Heart Failure. 22:1945-1960
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

This position statement from the Heart Failure Association of the European Society of Cardiology Cardio-Oncology Study Group in collaboration with the International Cardio-Oncology Society presents practical, easy-to-use and evidence-based risk stratification tools for oncologists, haemato-oncologists and cardiologists to use in their clinical practice to risk stratify oncology patients prior to receiving cancer therapies known to cause heart failure or other serious cardiovascular toxicities. Baseline risk stratification proformas are presented for oncology patients prior to receiving the following cancer therapies: anthracycline chemotherapy, HER2-targeted therapies such as trastuzumab, vascular endothelial growth factor inhibitors, second and third generation multi-targeted kinase inhibitors for chronic myeloid leukaemia targeting BCR-ABL, multiple myeloma therapies (proteasome inhibitors and immunomodulatory drugs), RAF and MEK inhibitors or androgen deprivation therapies. Applying these risk stratification proformas will allow clinicians to stratify cancer patients into low, medium, high and very high risk of cardiovascular complications prior to starting treatment, with the aim of improving personalised approaches to minimise the risk of cardiovascular toxicity from cancer therapies.

Details

ISSN :
18790844 and 13889842
Volume :
22
Database :
OpenAIRE
Journal :
European Journal of Heart Failure
Accession number :
edsair.doi...........5ae23c391549fd86ef6dd417c87ff069
Full Text :
https://doi.org/10.1002/ejhf.1920