Quality of Life and Coping in Patients with Acute Myeloid Leukemia (AML)

Intensification of treatment for AML resulted in a substantial improvement in longterm prognosis. As intensive therapy might be associated with high morbidity and most patients with AML eventually relapse, quality of life (QL) of patients has become an important parameter to be assessed. This study was designed to evaluate QL in patients with AML treated according to the protocol of the German AML-Cooperative Group (Munster). QL has been analyzed throughout therapy at 12 different time points by using the EORTC-QLQ C 30 questionnaire. Patients’ coping strategies were assessed by the Freiburg Questionnaire on Coping with Illness, patients’ individual perception of their disease and therapy by a semi-structured interview. 101 patients were enrolled in the protocol. For those patients having completed the courses of inpatient treatment (n=37), Physical functioning (p