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The preparation, characterization of Lupeol PEGylated liposome and its functional evaluation in vitro as well as pharmacokinetics in rats

Authors :
Junjie Hu
Guohua Zheng
Huali Liang
Hui Yao
Jun Zhang
Zhenpeng Qiu
Xinyan Chen
Xixi Hu
Source :
Drug Development and Industrial Pharmacy. 45:1052-1060
Publication Year :
2019
Publisher :
Informa UK Limited, 2019.

Abstract

Objective: The objective of this study was to enhance the solubility and bioavailability of Lupeol.Methods: Utilizing a thin-film dispersion method, we prepared Lupeol-loaded PEGylated liposomes an...

Details

ISSN :
15205762 and 03639045
Volume :
45
Database :
OpenAIRE
Journal :
Drug Development and Industrial Pharmacy
Accession number :
edsair.doi...........5b584d91083064a6fc31a0dca8ebdb12
Full Text :
https://doi.org/10.1080/03639045.2019.1569038