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A novel long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis

Authors :
wei gong
Fuman Qiu
Yinyan Li
Lei Yang
Yuanyuan Wang
Jianfeng Xian
Xin Zhang
Yifeng Zhou
Xinhua Wang
Guibin Qiao
Cuiyi Chen
Xincheng Gao
Jiachun Lu
Publication Year :
2020
Publisher :
Research Square Platform LLC, 2020.

Abstract

Background There is very little known about how long non-coding RNAs (lncRNAs) are associated with membrane proteins in lung cancer. The limbic system-associated membrane protein ( LSAMP ) has been reported to play a tumor suppressor role in a variety of cancers.Methods We aimed to explore the lncRNA associated with LSAMP and explore its effects on lung cancer.Results We found that Lnc-LSAMP-1 was significantly down-regulated in 170 cases of lung tumor tissues when compared to the adjacent non-cancerous tissues (p

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........5cf465d46e2a5e270922f781c79d6271
Full Text :
https://doi.org/10.21203/rs.2.21107/v1