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Characterization of the porcine FSCN3 gene: cDNA cloning, genomic structure, mapping and polymorphisms
- Source :
- Cytogenetic and Genome Research. 115:189-192
- Publication Year :
- 2006
- Publisher :
- S. Karger AG, 2006.
-
Abstract
- Fascin 3 (FSCN3)is a testis-specific actin-bundling protein involved in spermatid development. Here we describe the molecular characterisation of the porcine FSCN3 gene. The 1,800-bp cDNA sequence contains a 1,497-bp open reading frame encoding a protein of 498 amino acids with a calculated molecular mass of 56.2 kDa and an isoelectric point of 6.82. The porcine FSCN3 protein shares high identity with other mammalian FSCN3. The FSCN3 gene contains seven exons, spans approximately 9 kb, and maps to pig chromosome 18. We also identified 24 DNA polymorphisms.
Details
- ISSN :
- 1424859X and 14248581
- Volume :
- 115
- Database :
- OpenAIRE
- Journal :
- Cytogenetic and Genome Research
- Accession number :
- edsair.doi...........5f8a8c0a05cd367a69a8402865226e95