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A rank-based randomized phase II design when the phase III design is based on overall survival (OS)

Authors :
Yunro Chung
Maria Grazia Porro
Michael Shi
Weichao Bao
Fei Ma
Patricia A. Wood
William Mietlowski
Source :
Journal of Clinical Oncology. 32:6597-6597
Publication Year :
2014
Publisher :
American Society of Clinical Oncology (ASCO), 2014.

Abstract

6597 Background: Gan (2013) reported that approximately 27% of 120 randomized phase III trials with a primary endpoint of OS had statistically significant outcomes. Ratain (2005) suggests that the ...

Details

ISSN :
15277755 and 0732183X
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........600846f6dd443fc0202a30768df8ed42
Full Text :
https://doi.org/10.1200/jco.2014.32.15_suppl.6597