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Human cytomegalovirus expands a CD8+T cell population with loss ofBCL11Bexpression and gain of NK cell identity

Authors :
Renier J. Brentjens
Juliet N. Barker
Anthony F. Daniyan
Kento Tanaka
Rosa Sottile
Jean-Benoît Le Luduec
Joseph C. Sun
Colleen M. Lau
Katharine C. Hsu
M. Kazim Panjwani
Source :
Science Immunology. 6
Publication Year :
2021
Publisher :
American Association for the Advancement of Science (AAAS), 2021.

Abstract

CD8+ T cells not only are critical mediators of adaptive immunity but also may exhibit innate-like properties such as surface expression of NKG2C, an activating receptor typically associated with n...

Details

ISSN :
24709468
Volume :
6
Database :
OpenAIRE
Journal :
Science Immunology
Accession number :
edsair.doi...........601b7b886a6351f5dadfefad0ac4b5e5
Full Text :
https://doi.org/10.1126/sciimmunol.abe6968