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Correction of phase errors in quantitative water-fat imaging using a monopolar time-interleaved multi-echo gradient echo sequence
- Source :
- Magnetic Resonance in Medicine. 78:984-996
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- Purpose To propose a phase error correction scheme for monopolar time-interleaved multi-echo gradient echo water–fat imaging that allows accurate and robust complex-based quantification of the proton density fat fraction (PDFF). Methods A three-step phase correction scheme is proposed to address a) a phase term induced by echo misalignments that can be measured with a reference scan using reversed readout polarity, b) a phase term induced by the concomitant gradient field that can be predicted from the gradient waveforms, and c) a phase offset between time-interleaved echo trains. Simulations were carried out to characterize the concomitant gradient field-induced PDFF bias and the performance estimating the phase offset between time-interleaved echo trains. Phantom experiments and in vivo liver and thigh imaging were performed to study the relevance of each of the three phase correction steps on PDFF accuracy and robustness. Results The simulation, phantom, and in vivo results showed in agreement with the theory an echo time-dependent PDFF bias introduced by the three phase error sources. The proposed phase correction scheme was found to provide accurate PDFF estimation independent of the employed echo time combination. Conclusion Complex-based time-interleaved water–fat imaging was found to give accurate and robust PDFF measurements after applying the proposed phase error correction scheme. Magn Reson Med 78:984–996, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
- Subjects :
- medicine.diagnostic_test
Phase correction
Chemistry
Magnetic resonance imaging
Imaging phantom
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Nuclear magnetic resonance
Three-phase
Robustness (computer science)
medicine
Waveform
Radiology, Nuclear Medicine and imaging
030217 neurology & neurosurgery
Multi echo
Gradient echo
Subjects
Details
- ISSN :
- 07403194
- Volume :
- 78
- Database :
- OpenAIRE
- Journal :
- Magnetic Resonance in Medicine
- Accession number :
- edsair.doi...........6075c653504cdd5e3206ff7641506aac