ChemInform Abstract: One-Pot Synthesis of Trifluoromethylated Phthalans via Intramolecular Cyclization from 2-Alkynylbenzaldehydes

Authors :: Haizhen Jiang
Gang Zhao
Jian Hao
Lijun Xu
Source :: ChemInform. 45
Publication Year :: 2014
Publisher :: Wiley, 2014.
Abstract: Tandem nucleophilic/intramolecular cyclization of 2-(arylalkynyl)benzaldehydes and TmsCF3 offers an efficient one-pot synthesis of phthalans.

Subjects :: Tandem
Nucleophile
Chemistry
One-pot synthesis
Intramolecular cyclization
General Medicine
Combinatorial chemistry

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