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Construction of Biodegradable Polymer Scaffold by Photolithography
- Source :
- 2008 International Symposium on Micro-NanoMechatronics and Human Science.
- Publication Year :
- 2008
- Publisher :
- IEEE, 2008.
-
Abstract
- In this study, we succeeded in fine construction of the PLCL (poly-L-lactide-cocaprolactone) scaffold with micrometer range resolution using photolithography. PLCL is a biodegradable polymer which is used as a material of the scaffold to reproduce the blood vessel. Photolithography known as a technique of microfabrication was used for the processing of PLCL. By this technique, we fabricated a sheet-like PLCL scaffold which is patterned straight line ditches. Laminating the sheet-like scaffold, we fabricated microchannels in the PLCL scaffold. By the attachment of HUVECs in the channel, biocompatibility of the sheet-like PLCL scaffold was confirmed. It is expected to evaluate the behavior of cells in the scaffold.
Details
- Database :
- OpenAIRE
- Journal :
- 2008 International Symposium on Micro-NanoMechatronics and Human Science
- Accession number :
- edsair.doi...........60c7b8eca383b7cb33d20819e84cb28f