LITHOSPERMUM ERYTHRORHIZON SIEB. ET ZUCC. SUPPRESSES 3-HYDROXY-3-METHYL-GLUTARYL-COA REDUCTASE AND INDUCES LDL RECEPTOR EXPRESSION IN HEPG2 CELLS

Authors :: Sang-Yeon Kim
Hee Jin Jun
Sung-Hoon Kim
Jiyoung Kim
Jungae Jeun
Dal Woong Choi
Sung Joon Lee
Source :: Journal of Food Biochemistry. 35:997-1013
Publication Year :: 2011
Publisher :: Hindawi Limited, 2011.
Abstract: We examined the effects of Lithospermum erythrorhizon Sieb. et Zucc. (LE) on cholesterol metabolism in vitro. The ethanolic LE extract (ELE) had total polyphenolic and flavonoid contents of 353 ± 7 and 285 ± 51 mg/dL, respectively. The ELE inhibited Cu2+-mediated LDL oxidation at

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