Osteoarthritis and Hyperuricemia: Is There a Relationship?

Objective of the Review: To present the current information on the relations between osteoarthritis (OA) and hyperuricemia (HU). Key Points. Despite the fact that HU is frequently diagnosed in patients with OA, the pathogenic mechanisms of the relationship between these conditions have been studied poorly. Whether HU plays a role in development and progression of OA is still a matter of argument; still, HU can be an aggravating predictor of OA. Higher levels of uric acid are associated with more advanced Rg stages of OA. Conclusion. The article presents evidences of the relationship between uric acid concentration and development/progression and more complicated course of OA. Therefore, it is advisable to lower the uric acid concentration, which is likely to slow down OA progression. Keywords: osteoarthritis, hyperuricemia, uric acid.