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Revisiting the Fundamentals of Untargeted Data Analysis with Comprehensive Two-Dimensional Gas Chromatography (GC×GC): With Great Peak Capacity, There Must Also Come Great Responsibility
- Source :
- LCGC North America. :105-111
- Publication Year :
- 2023
- Publisher :
- Multimedia Pharma Sciences, LLC, 2023.
-
Abstract
- This article provides a general overview of untargeted analysis using comprehensive two-dimensional gas chromatography (GC×GC), while revisiting some fundamental aspects of method development. The original definition of chemometrics is also revised according to the latest developments of the field. We discuss how GC×GC has become an important backbone for new strategies in separation science, especially in multivariate data analysis. The concept of pixel is also revisited, as an important pixel-based data processing method, namely the Fisher ratio proposed by Synovec and coworkers, has been successfully implemented in important software for GC×GC.
- Subjects :
- Analytical Chemistry
Subjects
Details
- ISSN :
- 19391889 and 15275949
- Database :
- OpenAIRE
- Journal :
- LCGC North America
- Accession number :
- edsair.doi...........64f3d8d053e4c14f635b4681a3d38605
- Full Text :
- https://doi.org/10.56530/lcgc.na.yz7686f4