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Revisiting the Fundamentals of Untargeted Data Analysis with Comprehensive Two-Dimensional Gas Chromatography (GC×GC): With Great Peak Capacity, There Must Also Come Great Responsibility

Authors :
Leandro Wang Hantao
Source :
LCGC North America. :105-111
Publication Year :
2023
Publisher :
Multimedia Pharma Sciences, LLC, 2023.

Abstract

This article provides a general overview of untargeted analysis using comprehensive two-dimensional gas chromatography (GC×GC), while revisiting some fundamental aspects of method development. The original definition of chemometrics is also revised according to the latest developments of the field. We discuss how GC×GC has become an important backbone for new strategies in separation science, especially in multivariate data analysis. The concept of pixel is also revisited, as an important pixel-based data processing method, namely the Fisher ratio proposed by Synovec and coworkers, has been successfully implemented in important software for GC×GC.

Subjects

Subjects :
Analytical Chemistry

Details

ISSN :
19391889 and 15275949
Database :
OpenAIRE
Journal :
LCGC North America
Accession number :
edsair.doi...........64f3d8d053e4c14f635b4681a3d38605
Full Text :
https://doi.org/10.56530/lcgc.na.yz7686f4