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Assessment of iodine availability and its influence on hematological characteristics of iodine prophylaxis in pregnant women living in the iodine deficient natural environment

Authors :
V N Petrova
E A Troshina
F M Abdulkhabirova
A V Sekinaeva
E I Vinogradova
S V Petrova
Source :
Problems of Endocrinology. 56:21-25
Publication Year :
2010
Publisher :
Endocrinology Research Centre, 2010.

Abstract

The objective of the present study was to evaluate effects of iron deficiency anemia in pregnant women on the effectiveness of iodine prophylaxis; the secondary objective was to develop standard prophylactic iodine dose schedule for these patients. The study included two groups of pregnant women treated either with a daily dose of 200 mcg potassium iodide (group 1, n=32) or with 300 mcg potassium iodide/day (group 2, n=68). In all of them, blood TSH, free thyroxin and antithyroid peroxidase antibody levels were measured along with iodine excretion in urine. Thyroid volume was determined by ultrasound. Diagnosis of anemia was based on the results of clinical blood analysis including hemoglobin level, erythrocyte count, hematocrit, and mean hemoglobin content of red blood cells. Iron deficiency was estimated from serum iron and ferritin (SF) levels. Treatment with potassium iodide during pregnancy resulted in a significant increase of the median urine iodine level to 260.9 mcg/l and 143.7 mcg/l in groups 1 and 2 respectively (p

Details

ISSN :
23081430 and 03759660
Volume :
56
Database :
OpenAIRE
Journal :
Problems of Endocrinology
Accession number :
edsair.doi...........6769c45f718ecb50f624c44af0711748
Full Text :
https://doi.org/10.14341/probl201056321-25