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Assessment of iodine availability and its influence on hematological characteristics of iodine prophylaxis in pregnant women living in the iodine deficient natural environment
- Source :
- Problems of Endocrinology. 56:21-25
- Publication Year :
- 2010
- Publisher :
- Endocrinology Research Centre, 2010.
-
Abstract
- The objective of the present study was to evaluate effects of iron deficiency anemia in pregnant women on the effectiveness of iodine prophylaxis; the secondary objective was to develop standard prophylactic iodine dose schedule for these patients. The study included two groups of pregnant women treated either with a daily dose of 200 mcg potassium iodide (group 1, n=32) or with 300 mcg potassium iodide/day (group 2, n=68). In all of them, blood TSH, free thyroxin and antithyroid peroxidase antibody levels were measured along with iodine excretion in urine. Thyroid volume was determined by ultrasound. Diagnosis of anemia was based on the results of clinical blood analysis including hemoglobin level, erythrocyte count, hematocrit, and mean hemoglobin content of red blood cells. Iron deficiency was estimated from serum iron and ferritin (SF) levels. Treatment with potassium iodide during pregnancy resulted in a significant increase of the median urine iodine level to 260.9 mcg/l and 143.7 mcg/l in groups 1 and 2 respectively (p
- Subjects :
- medicine.medical_specialty
medicine.diagnostic_test
business.industry
Anemia
Endocrinology, Diabetes and Metabolism
chemistry.chemical_element
Physiology
Urine
Hematocrit
medicine.disease
Iodine
Iodine deficiency
Excretion
Endocrinology
chemistry
Iron-deficiency anemia
Internal medicine
Serum iron
Medicine
business
Subjects
Details
- ISSN :
- 23081430 and 03759660
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Problems of Endocrinology
- Accession number :
- edsair.doi...........6769c45f718ecb50f624c44af0711748
- Full Text :
- https://doi.org/10.14341/probl201056321-25