Correlation between the menstrual cycle and the onset of recurrent aphthous stomatitis

Background: The association between recurrent aphthous stomatitis (RAS) and the menstrual cycle is not clearly reported in the scientific literature. Aim: The aim of this study was to find the association between the onset of RAS and various phases of the menstrual cycle. Materials and Methods: Data regarding the onset of RAS were collected from 140 female participants during various phases of the menstrual cycle. Results: Out of 140 participants, 30 reported with the incidence of RAS during the 3 months of evaluation. Out of those 30 participants, 10 had incidence of ulcers during the third week after menstruation. Conclusions: Hormonal factors may play a role in the clinical manifestation of RAS.