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Novel inhibitors of nicotinamide phosphoribosyl transferase and their evaluation in combination with bortezomib

Authors :
Subramanya Hosahalli
Kishore Narayanan
Sreevalsam Gopinath
Sunil Kumar Panigrahi
Anirudha Lakshminarasimhan
Dinesh Chikkanna
Murali Ramachandra
Narasimha Rao K
Anuradha Ramanathan
Vinayak Khairnar
Raghuveer Ramachandra
Chetan Pandit
Sumalatha Rani
Karthikeyan S
Source :
Journal of Clinical Oncology. 32:e19566-e19566
Publication Year :
2014
Publisher :
American Society of Clinical Oncology (ASCO), 2014.

Abstract

e19566 Background: Nicotinamide phosphoribosyl transferase (NAMPT) is the enzyme that catalyzes the rate limiting step in the salvage pathway of Nicotinamide Adenine Dinucleotide (NAD) biosynthesis...

Details

ISSN :
15277755 and 0732183X
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........6890341ed2de7a1192cd1f706c505c30
Full Text :
https://doi.org/10.1200/jco.2014.32.15_suppl.e19566