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Disparities in speed to BMT consult and allograft in 279 adults with AML

Authors :
Warren Benjamin Fingrut
Boglarka Gyurkocza
Eric Davis
Jessica Flynn
Andromachi Scaradavou
Stephanie Chinapen
Kristine Naputo
Sean Quach
Christina Cho
Sergio Giralt
Esperanza Bouza Papadopoulos
Miguel-Angel Perales
Brian C. Shaffer
Ioannis Politikos
Juliet Naomi Barker
Source :
Journal of Clinical Oncology. 40:6523-6523
Publication Year :
2022
Publisher :
American Society of Clinical Oncology (ASCO), 2022.

Abstract

6523 Background: Whether patient (pt) ancestry impacts the time to BMT is not established. Methods: We hypothesized that non-European (non-EURO) ancestry AML pts are at increased risk of delayed time to transplant. Thus, we analyzed time to allograft (Allo) by ancestry defining delayed (late) times as: Allo Indication to BMT Consult (Ind. – Consult) > 90 days, Consult – BMT > 120 days & Allo Indication to BMT (Ind. - BMT) > 180 days. We studied pts < 70 yrs transplanted 1/2016-7/2021. Results: In 279 AML pts (median 56 yrs, range 19-69), BMT indication was date of diagnosis if ELN 2017 intermediate/ high risk &/or high risk mutations &/or sAML in 261 (94%) pts, or date of refractory/ relapsed disease in 18 (6%) pts. European (EURO) pts (n = 195, 70%; median 60 yrs) were older than non-EURO pts (n = 84, 30%; median 49 yrs), p

Subjects

Subjects :
Cancer Research
Oncology

Details

ISSN :
15277755 and 0732183X
Volume :
40
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........6942214715fddc963424a0fe4959c747
Full Text :
https://doi.org/10.1200/jco.2022.40.16_suppl.6523