227 – Different pattern of surface shape deformity of thalamus between obsessive–compulsive disorder and schizophrenia

gained by manual segmentation. Gyral pattern, absolute and relative measures and asymmetries were analyzed. Results: Right HG was tendentially more often duplicated than left HG in the hallucinating patients. Concerning asymmetry, in patients the normal left-greater-than-right laterality of HG and the PT was attenuated, without difference between the groups. There were no statistical group effects for any volume measure. But, in the hallucinating group, right HG white matter was significant bigger than the left sided; this not the case in any other group. Conclusions: Volumetric studies on the temporal lobe in hallucinations are unequivocal, maybe due to only very small if at all differences in macro structural markers. In a sample with demonstrated microstructural changes we did not find differences between the groups with only suggested evidence for white matter plasticity associated with hallucinations.