A prospective study on the effect of endoxifen concentration and CYP2D6 phenotypes on clinical outcome in early stage breast cancer patients receiving adjuvant tamoxifen

Authors :: Carolien H. Smorenburg
Maartje Los
Henk-Jan Guchelaar
Hans Gelderblom
Vincent O. Dezentjé
A B Sanchez-Spitman
Lynn Jongen
Erdogan Batman
Jesse J. Swen
Dirk Jan A.R. Moes
Patrick Neven
Source :: Journal of Clinical Oncology. 36:523-523
Publication Year :: 2018
Publisher :: American Society of Clinical Oncology (ASCO), 2018.
Abstract: 523Background: It has been postulated that endoxifen levels are better predictors of tamoxifen efficacy than CYP2D6 phenotype. Although in a retrospective study an endoxifen threshold of 5.9 ng/ml ...

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