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RETRACTED: From Stem Cell to Red Blood Cells In Vitro: 'The 12 Labors of Hercules'

Authors :
Luc Douay
Source :
Clinics in Laboratory Medicine. 30:391-403
Publication Year :
2010
Publisher :
Elsevier BV, 2010.

Abstract

This article describes the research in progress that will permit the large-scale production of human red blood cells from hematopoietic stem cells. It also discusses the current state of this research, suggests the obstacles to be overcome to pass from the laboratory model to clinical practice, and analyzes the possible indications in the medium and long term. The potential interest of pluripotent stem cells as an unlimited source of red blood cells is considered. If it succeeds, this new approach could mark a considerable advance in the field of transfusion.

Details

ISSN :
02722712
Volume :
30
Database :
OpenAIRE
Journal :
Clinics in Laboratory Medicine
Accession number :
edsair.doi...........6a8f30aa7f77b52549d1359cf3547864
Full Text :
https://doi.org/10.1016/j.cll.2010.02.003