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Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff

Authors :
Manal F Cheema
Zeeshan Butt
Samreen Gilani
Sidra Shafiq
Shafiq Cheema
Manash K Das
Source :
American Journal of Hypertension.
Publication Year :
2023
Publisher :
Oxford University Press (OUP), 2023.

Abstract

Background In the original SPRINT article, age was categorized at 75 years, which was contrary to many previous clinical trials which is at 60 years. Methods The SPRINT trial randomized 9,361 hypertensive patients to a target blood pressure of Results Intensive treatment reduced primary outcome significantly in both Conclusions Intensive blood pressure control is beneficial for elderly patients (age ≥60 years), albeit with increased risk of adverse events.

Subjects

Subjects :
Internal Medicine

Details

ISSN :
19417225 and 08957061
Database :
OpenAIRE
Journal :
American Journal of Hypertension
Accession number :
edsair.doi...........6aac4821b32b81b8842a4e951a674597
Full Text :
https://doi.org/10.1093/ajh/hpad039